Aug 15, Frequently, patients do not volunteer problems related to sexuality, and SSRIs also cause other sexual dysfunction that can affect libido and. Depression is a common mental health problem that is often treated by a class of medication called serotonin-specific reuptake inhibitors, or SSRIs. Examples of. Sexual side effects and one's libido are an important issue when it comes to lower sexual side-effect profiles than other commonly prescribe antidepressants. Sexual side effects in both genders. Verified by Psychology Today. Breaking up with your partner can be downright painful. Outchoff, K. Patience is key when managing sexual side effects. Even with these potential side effects, keep taking your medications for your mental health. Algorithm for managing medication-induced sexual dysfunction.