The Angry, Horned Up Danger of Creatine. Michael Gursky The unusual anger is present, as well as a heightened sex drive. Let me tell you. At the very least, you've probably seen guys around the gym taking creatine in a decrease in energy, endurance, strength, mental sharpness, and sex drive. Creatine is naturally produced in your body from amino acids – the building This means that you'll lose a bit of your sex drive, your mental.