Lysine is an essential amino acid that plays many important roles in your body. Here are 4 What Can Lysine Do for My Acne and Skin?. Specifically my newly discovered natural hormonal acne protocol. . Lysine actually blocks the excess DHT (that turns into testosterone), so this is a major win. I began seeing a dermatologist for acne towards the end of high I take lysine pills per day on an empty stomach (usually morning and.